Quotations About HGH From
The International Medical Community

Articles on this page giving medical opinions on HGH Therapy.
Other Misc Studies I've found on-line

The List of Medical and Scientific Articles presented here is for educational and informational purposes only. No dietary supplement product discussed in this website is intended to treat, cure, diagnose or mitigate any disease.

Thousands of Doctors and health care professionals worldwide now believe that increasing Human Growth Hormone levels may be one of the most important factors in Health, Wellness, and Fitness yet discovered. By increasing your levels of HGH, you may be able to enjoy these same health, wellness, and fitness benefits.
What follows are quotes from the medical profession, that can be accessed by the links below, and a Bibliography for your further reference.

1996 New England Journal of Medicine
Dr. George Merriam, University of Washington in Seattle- National Institute of Aging studies on growth hormone
Doctor Edmund Chein
Doctors Thierry Hertaghe and Vince Giampap
Grace Wong of Genetech
Sahlgrenska Hospital in Sweden
Thomas C. Welbourne of Louisiana State University Collage of Medicine
Vladimir Dilman, PH.D
Silvio Inzucchi of Yale University
Dr. Robert Kerr, San Gabriel, California
Dr. Julian Whitaker of Newport Beach, California
David Clemmons, Chief of Endocrinology,University of North Carolina School of Medicine
Daniel Rudman, M.D., Medical College of Wisconsin
Dr. Eve Van Cauter, GH researcher, University of Chicago Medical Center
Dr. Lawrence Dornan, member of the American Academy of Anti-Aging
Dr. Jorgensen and Dr. Christian of Copenhagen, Denmark, in European Journal of Endocrinology, 1994

Doctor Edmund Chein from 1994 to 1996 treated over 800 people with HGH replacement therapy. And the results were published in Doctor Ronald Klatz's 1997 book "Grow Young With HGH". These results demonstrated to scientists and the public, the safety and efficacy of HGH in improving a broad array of human health parameters in adults
Doctors Thierry Hertaghe and Vince Giampapa report that the latest European research indicates that Human Growth Hormone (HGH) can go beyond the current antioxidant based anti-aging remedies in slowing, preventing and reversing aging at the cellular level.
Grace Wong of Genetech has shown that as we age cell proteins suffer ever accumulating damage. This is, in large part, caused by the ever-increasing incidence of free radicals released during normal cellular activity. Wong says that HGH can actually activate a cellular defense force of protease inhibitors. So even if high levels of free radicals can't be avoided, the protease inhibitors prevent the free radicals from triggering cell destructive protease. Thus, unlike antioxidants, HGH does not just reduce cellular damage, it can actively promote the healing and regeneration of cells!
After six months of HGH treatment at Sahlgrenska Hospital in Sweden HGH deficient adults lost 20% of their body fat. Most of this fat loss occurred in abdominal fat, reduced by 30% compared with a 13% reduction in peripheral fat. (e.g. arm and leg) It is abdominal fat that is strongly correlated with increased incidence of heart attack., hypertension and diabetes.
Thomas C. Welbourne of Louisiana State University Collage of Medicine in Shreveport, conducted a study that showed that a surprisingly small dose of Glutamine (Major component of our "AgeForce™" formula) raised HGH levels more than four times the amount of patients on a placebo. Even more exciting, age did not diminish the responses.
Vladimir Dilman, PH.D. “Hormones are vital for repairing and regulating our bodily functions. As we age, though the body produces lower levels of hormones, which can result in disastrous effects, including the decline of self-repair and self-regulation. Hormone replacement therapy, a frequent component of any anti-aging treatment, helps to reset the body’s hormonal clock and thus can reverse of delay the effects of aging. If our hormones are being produced at youthful levels, in a very real sense the cells of our bodies are stimulated to be metabolically active and thus, the entire body stays young.”
Silvio Inzucchi of Yale University wrote in the January 15, 1997 issue of Hospital Practice, “Growth hormone deficiency is not formally recognized as a specific clinical syndrome, typified by decreased muscle mass, increased body fat (predominantly at intra-abdominal sites)
Dr. Robert Kerr (San Gabriel, California, treated over 8,000 athletes in the course of his practice, prescribing HGH. Kerr said his patients took HGH for only three to six weeks. In that time, bodybuilders claimed their results lasted up to 12 months. Some athletes claimed to have gained up to 40 pounds in six weeks while reducing their body fat.
Dr. Julian Whitaker of Newport Beach, California has been prescribing HGH to his elderly patients, as well as taking it himself. He states, “I have not seen anything that even comes close to the restorative power of HGH supplementation”. In Whitaker’s opinion, HGH is most effective in combating the effects of chronic diseases that involve muscle wasting: stroke, chronic obstructive pulmonary disease, and AIDS,
1996 New England Journal of Medicine – Patients treated with HGH who had moderate-to-severe heart failure, increased the thickness of the left ventricular wall, enhanced the ability of the heart to contract and pump out blood, reduced the oxygen requirement of the heart, improved exercise capacity, clinical systems, and the patients quality of life.
David Clemmons, chief of Endocrinology at the University of North Carolina School of Medicine in Chapel Hill, believes that HGH is a promising treatment for emphysema and other chronic obstructive pulmonary diseases.
Daniel Rudman, M.D., Medical College of Wisconsin. "The effects of six months of growth hormone on lean body mass and adipose-tissue mass were equivalent in magnitude to the changes incurred during 10 to 20 years of aging."
Dr. Eve Van Cauter, GH researcher, University of Chicago Medical Center. "All of these ideas about treating people with growth hormone have been directed towards people sixty-five and older. If you look at the data, people have so-called 'elderly' levels by age forty. Perhaps we should be giving GH replacement therapy earlier rather than attempting to treat tissues that have seen little or no growth hormone for decades."
Dr. Lawrence Dornan, member of the American Academy of Anti-Aging "It stops the aging process in the body and reverses many of the problems that are caused by aging, such as wrinkling skin, increased body fat, decreased muscle mass, increased cholesterol, decreased stamina and energy, decreased mental function, impaired neurological functions such as Parkinson's and Multiple Sclerosis. IGF-1 or growth hormone is truly an amazing substance which is both safe and effective with no known side effects unless it's used in an overdose manner."
Dr. George Merriam, University of Washington in Seattle-National Institute of Aging studies on growth hormone " There is no evidence suggesting that this [growth hormone] replacement therapy causes any unfavorable long term side effects... a complete absence of side effects."
Dr. Jorgensen and Dr. Christian of Copenhagen, Denmark, in European Journal of Endocrinology, 1994 "Replacement therapy with Growth Hormone has shown beneficial and normalizing effect on parameters such as cardiac and renal function, thyroid hormone metabolism, bone metabolism, sweat secretion, total and regional fuel metabolism and psychological well being"

Human Growth Hormone References

Boericke, Wm. M.D., Homeopathic Materia Medica. Philadelphia, PA, Boericke & Runyon, (1927).

Boxenbaun, H. Neafsey, PJ, Fournicer,DJ. Hormesis, Gompertz. Functions, and Risk Assessment. Drug Metabolism Review 19: 195-229, 1998.

Brewitt, Barbara, Ph.D. "HIV-AIDS Clinical Homeopathic Trial Status / Summary of Clinical Studies on HIV". Biomedical Exploration, LLC / Biomed Comm Inc. (June 1997).

Davis, Adelle, M.S. Let’s Get Well. New York: The New American Library, Inc., (1972).

Demarco, Carolyn, M.D. "Anti-Aging Breakthrough— Homeopathic Growth Factors." Let’s Live, (March, 1998).

Gelato, M.C. MD, Ph.D. Aging and immune function: A possible role for growth hormone. Hormone Research, (1996) 45:46-49.

Hickey, R.J. Radiation Epidemiology, Extrapolation, and Opinion (letter). Chemical Engineering News, 23, pages 2 - 3. January 1989.

Iovino M. et al: Repetitive growth hormone-releasing hormone administration restores the attenuated growth (GH) response to GH—Releasing hormone testing in normal aging. Journal Clinical Endocrine Metabolism, 69:910 (1989).

Jamieson, J.; Dorman L.E. D.O. Growth Hormone: Reversing Human Aging Naturally, The Methuselah Factor. E. Canaan, CT: Safe Goods and Longevity News Network, (1997).

Kahn, C. "No More Slow Death." Longevity, February 1990.

Kelijman M: Age-related alterations of the growth hormone / insulin-like growth factor 1 axis. Geriatric Journal of American Society 39:295, (1991).

Kunz, R.M., Jeffery, M.D. Editor. The American Medical Association Family Medical Guide. New York: Random House, (1982).

Marion, B., Joseph. Anti-Aging Manual. South Woodstock, Conn., Informative Pioneers, (1995;1996).

Murray, Michael T. N.D. Encyclopedia of Nutritional Supplements. Rocklin, CA: Prima Publishing, (1996).

Palmer, B.J., Ph.C., D.C. History in the Making. Davenport, Iowa. Palmer College Press, (1957).

Pearson, Durk M.S. and Shaw, Sandy M.S. Life Extension: A Practical Scientific Approach. New York: Warner Books, (1983).

Phillips, L.S.; Harp. J.B; Goldstein, S; Klein, J; and Pao, C.I. Regulation and action of insulin-like growth factors at the cellular level. Proceedings of the Nutrition Society 49:451-458, (1990).

Prinz, Petal. Plasma growth hormone during sleep in young and aged men." Journal of Gerontology, 38:519, (1983).

Riley, D., M.D. "Proving/Homeopathic Study of Insulin–like Growth Factor I (IGF-1)", Integrative Medicine Institute, Santa Fe, New Mexico, (1997).

Rudman, D., M.D., et al. Effects of human growth hormone in men over 60 years old. New England Journal of Medicine, 323 (1990): 1-6.

Rudman, D., M.D. Growth hormone, body composition, and aging. Journal of the American Geriatrics Society 33 (1985): 800-07.

Rudman, D.; Kutnen, MH; Rogers, CM. Impaired growth hormone secretion in the adult population: Relation to age and adiposity. Journal of Clinical Investigation (1981): 67: 1361-1366.

Schwartz, Edward, Ph.D. "The Million Dollar Question— The Real Question in Homeopathy Is: Does a Substance That Has Been Repeatedly Diluted Really Work?" Health Way (March 1996).

Weiss, R. "A Shot at Youth". American Health, (Nov-Dec. 1993)

Con opinions regarding effectiveness of HGH Therapy.

"Although growth hormone levels decline with age, it has not been proven that trying to maintain the levels that exist in young persons is beneficial." QuackWatch

References

1. Vance ML. Growth hormone for the elderly? New England Journal of Medicine 323:52-54, 1990.
2. Pearson D, Shaw S. Life Extension: A Practical Scientific Approach. New York: Warner Books, 1982.
3. Barrett S. Book Review: Life Extension: A Practical Scientific Approach. ACSH News and Views 4(5):14-15, 1983.
4. Yetiv J. Popular Nutritional Practices: A Scientific Appraisal. Toledo, Ohio: Popular Medicine Press, 1986, pp. 82-101.
5. Weider to pay at least $400,000 in consumer redress and research grants under Federal Trade Commission agreement. FTC News release, Aug 19, 1985.
6. Franchisor of food supplement stores prohibited from making false claims, under consent agreement with FTC. FTC News release, Jan 4, 1988.
7. General Nutrition Inc. agrees to pay $2.4 million civil penalty to settle charges it violated two previous FTC orders. FTC News release, April 28, 1994.
8. Nature's Bounty to pay $250,000 redress as part of settlement with FTC over supplement claims. FTC News release, April 27, 1995.
9. 3,044 victims of weight-loss clinics fraud case to get partial refunds, following FTC law enforcement action. FTC News release, April 10, 1997.
10. von Nostitz G and others. Magic muscle pills!! Health and fitness quackery in nutrition supplements. New York City Department of Consumer Affairs, 1992.
11. Rudman D and others. Effects of human growth hormone on men over 60 years old. New England Journal of Medicine 323:1-6, 1990.
12. Time in a bottle? Dateline NBC, March 6, 2001.
13. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for growth hormone use in adults and children -- 2003 update. Endocrine Practice 9-65-76, 2003.
14. AACE guidelines support proper use of growth hormone replacement therapy. American Association of Clinical Endocrinologists news release, Sept 9, 1999.
15. Butler RN. Some notes on "anti-aging" programs. Quackwatch
16. Drazen JM. Inappropriate advertising of dietary supplements. New England Journal of Medicine 348:777-778, 2003.
17. Vance ML. Retrospective: Can growth hormone prevent aging? New England Journal of Medicine 348:779-780, 2003.
18. Blackman MR and others. Growth hormone and sex steroid administration in healthy aged women and men: a randomized controlled trial. JAMA 288:2282-2292, 2002.
19. Papadakis MA and others. Growth hormone replacement in older men improves body composition but not functional ability. Annals of Internal Medicine 124:708-716, 1996.
20. Taaffe DR and others. Effect of recombinant human growth hormone on the muscle strength response to resistance exercise in elderly men. Journal of Clinical Endocrinology and Metabolism 79:1361-1366, 1994.

"Misc Studies I've found around the net" Zaak

HGH 'Doubles Death Rate' among Critically Ill

Human growth hormone (HGH) was once considered a major breakthrough in intensive care medicine as it combated the muscle wastage experienced by patients who spend long periods immobilised in bed. However, results of a study by researchers at Kuopio University Hospital in Finland have revealed that treating critically ill patients with HGH could significantly increase their risk of death.

The researchers conducted two studies involving 247 Finnish patients and 285 patients in other European countries who had been in intensive care for 5 to 7 days and who were expected to need intensive care for at least 10 days. The patients had undergone cardiac surgery, abdominal surgery, or suffered multiple trauma, or acute respiratory failure.

Results of the Finnish study showed that the death rate of those treated with growth hormone was 39% - nearly double that of those not treated with the hormone. Meanwhile the respective death rates in the multinational study were 44% and 18%. What's more, for survivors, treatment with HGH seemed to increase the length that patients needed to stay in intensive care or on a respirator.

SOURCE/REFERENCE: New England Journal of Medicine 1999; 341: 785-792

[KIGS/KIMS Outcomes Research, Pharmacia AB, Stockholm, Sweden]
Data concerning visits to the doctor, number of days in hospital, and amount of sick leave were obtained from patients included in KIMS (Pharmacia International Metabolic Database), a large pharmacoepidemiological survey of hypopituitary adults with GHD, for 6 months before GH treatment and for 6-12 months after the start of treatment. Assistance required with normal daily activities was recorded at baseline and after 12 months of GH therapy. Quality of life (QoL) (assessed using a disease-specific questionnaire, QoL-Assessment of GHD in Adults) and satisfaction with physical activity during leisure time were also assessed. For the total group (n = 304), visits to the doctor, number of days in hospital, and amount of sick leave decreased significantly (P < 0.05) after 12 months of GH therapy. Patients also needed less assistance with daily activities, although this was significant (P < 0.01) only for the men. QoL improved after 12 months of GH treatment (P < 0.001), and both the amount of physical activity and the patients' satisfaction with their level of physical activity improved after 12 months (P < 0.001). In conclusion, GH replacement therapy, in previously untreated adults with GHD, produces significant decreases in the use of healthcare resources, which are correlated with improvements in QoL. [Hernberg-Stahl E, Luger A, Abs R, Bengtsson BA, Feldt-Rasmussen U, Wilton P, Westberg B, Monson JP; KIMS International Board., KIMS Study Group. Pharmacia International Metabolic Database, "Healthcare consumption decreases in parallel with improvements in quality of life during GH replacement in hypopituitary adults with GH deficiency," J Clin Endocrinol Metab. 2001 Nov;86(11):5277-81]

Department of Medical Sciences, University Hospital, Uppsala, Sweden:

The safety and effects of a fixed low dose of growth hormone (GH), 0.17 mg/day was evaluated for 3 months, on glucose metabolism, serum lipids, body composition and cardiac function in 53 GH deficient adults aged 18-78 years. At 3 months, serum levels of insulin-like growth factor (IGF)-I, IGF binding protein (IGFBP)-3 and lipoprotein (a) and lean body mass were increased (P<0.05). Total and low density lipoprotein cholesterol levels and fat mass were reduced (P<0.05). There was an increase in the serum glucose value at 120 min after an oral glucose tolerance test performed at 3 months (P<0.05), no other changes in glucose metabolism or in cardiac function were noted. Side-effects were few and mild. This fixed low-dose regime resulted in improvements in body composition and lipid profile, without causing serious side effects. This is therefore a valid method to institute GH replacement in adults. [Gillberg P, Bramnert M, Thoren M, Werner S, Johannsson G, "Commencing growth hormone replacement in adults with a fixed low dose. Effects on serum lipoproteins, glucose metabolism, body composition, and cardiovascular function," Growth Horm IGF Res. 2001 Oct;11(5):273-81]

Department of Medicine, University of Bochum, Bochum, Germany:

We examined long-term changes in BMD with GH treatment in GH-deficient adults over a period of 6 years. Twelve GH-deficient patients (four women, eight men) with a mean age of 42.5 years (range 24-61 years) at the beginning of GH replacement. Eleven patients suffered in addition from LH/FSH insufficiency, eight from TSH insufficiency and eight from ACTH insufficiency. Before the start of GH substitution, the insufficient anterior pituitary axes were fully substituted for an average of 9.8 years (range 2-22 years). Average daily GH dose was 2.4 IU (SD 0.86). BMD and bone area were measured at annual intervals at the lumbar spine and at the proximal femur using dual-X-ray absorptiometry. Under GH substitution, serum insulin-like growth factor I concentrations increased by 140 microg/l compared to pretherapeutic values (P = 0.0003). BMD at the lumbar spine increased by 0.16 g/cm2 (P = 0.0005), corresponding to a mean increase of 15.9% or an increase of the BMD Z-score by 1.53 SD. Increases in BMD were independently observed from years 3 to 6 by a mean of 5.8% (P = 0.0087). This increase was paralleled by an increase in the area of the lumbar vertebrae. Bone area also increased at selected sites of the proximal femur, but there was no consistent increase in BMD at the proximal femur. GH therapy in GH-deficient adults is able to progressively increase BMD and bone area at the lumbar spine over a period of at least 6 years. [Clanget C, Seck T, Hinke V, Wuster C, Ziegler R, Pfeilschifter J, "Effects of 6 years of growth hormone (GH) treatment on bone mineral density in GH-deficient adults," Clin Endocrinol (Oxf). 2001 Jul;55(1):93-9]

lso See:

HGH, What Doctors Say II
HGH, The Master Hormone of Youth

Anti-Aging: A case study!