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agonists:
It is known that several substances are effective agonists of GH (i.e. they stimulate the pituitary gland's release of GH). These are certainly more proven and a better route to take. Here one may find Ronald Klatz MD's book, Grow Young with HGH (published by Harper Collins), a useful reference guide; in it he lists several beneficial substances.
But in most cases the best that can be expected is about a 30% night time improvement of GH levels, sounds impressive in-itself until one realizes that s.c. injections of GH can make improvements of up to 600%! The best proven oral agonist of GH was Gamma Hydroxy Butyrate (GHB), and it was no accident that GHB's sleep inducing affects must have contributed to its up-to 300% improvement of GH levels (as clinically studied by the Japanese). However the FDA and DEA ban on GHB because of its so-called "Date Rape" properties (and the UN's enforcement of that unscientific evidence in many other countries around the world), effectively rules out that "miracle molecule." |
amino
acids:
Organic compounds that generally contain an amino (-nh2) and
a carboxyl (-cooh) group.
Twenty alpha-amino acids are the subunits which are polymerised
to
form
proteins.
amino group:
An -NH2 group. Organic compounds which have this group are called
amines.
bovine
growth hormone:
A hormone secreted by the bovine pituitary gland. It is used
to increase milk production by improving the feed efficiency
in dairy cattle.
growth
factor:
A complex family of polypeptide hormones
or biological factors
that are produced by the body to control growth, division and
maturation of blood cells by the bone marrow. They regulate
the division and proliferation of cells and influence the growth
rate of some cancers. These factors occur naturally but some
can be synthesized using molecular biology techniques and are
used clinically to stimulate normal white cell production following
chemotherapy or bone
marrow transplantation.
Examples
include epidermal growth factor, platelet-derived growth factor,
fibroblast growth factor. Insulin and somatomedin are also growth
factors, the status of nerve growth factor is more uncertain.
Perturbation of growth factor production or of the response
to growth factor is important in neoplastic transformation.
growth
hormone:
Polypeptide (191 amino acids) produced by anterior pituitary
that stimulates liver to produce somatomedins 1 and 2.
growth
hormone regulating hormone:
Hypothalamic hormones that induce (somatoliberin) or inhibit
(somatostatin) the release of growth
hormone (somatotropin).
Growth
Hormone-Releasing Hormone (GHRH):
Hormone produced in the hypothalamus that promotes production
of Human Growth Hormone. [See Human Growth Hormone]
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HGH:
Human Growth Hormone is often referred to as "HGH".
Homeopathy:
Homeopathy
is a non-toxic system of medicine used to treat illness and
relieve discomfort of a wide variety of health conditions. It
is practiced by licensed physicians and other qualified prescribers
in many regions of the world, including Europe, Asia, the U.K.,
and the U.S.
hormone:
A naturally occurring substance secreted by specialized cells
that affects the metabolism or behavior of other cells possessing
functional receptors for the hormone. Hormones may be hydrophilic,
like insulin, in which case the receptors are on the cell surface
or lipophilic, like the steroids, where the receptor can be
intracellular.
human
growth hormone:
A protein produced in the pituitary gland that stimulates the
liver to produce somatomedins, which stimulate growth of
bone
and muscle.
Also
called Somatotropin, HGH is a protein-like
hormone that many researchers believe has greater capacity to
prevent and reverse aging than any other substance. Under a
physician's care, HGH replacement therapy is administered with
daily injections. Alternatively or in addition, HGH releasers
are widely available without prescription, including arginine,
ornithine, and other amino acids taken orally as supplements.
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IGF
- Insulin like Growth Factor:
Insulin like growth factors I and II are polypeptides with considerable
sequence similarity to insulin.
They
are capable of eliciting the same biological responses, including
mitogenesis in cell culture. On the cell surface, there are
two types of insulin like growth factor receptor, one of which
closely resembles the insulin receptor (which is also present).
Insulin
like growth factor I = somatomedin A = somatomedin C
Insulin like growth factor II = MSA (Multiplication stimulating
activity).
Insulin like growth factor 1 is released from the liver in response
to growth hormone.
Acronym: IGF
mucosa:
The soft tissue internal surfaces of the mouth, tongue, and
cheek
peptide:
A compound of two or more amino acids
where the alpha carboxyl group of one is bound to the alpha
amino group of another.
Link
between two amino acids; peptide also refers to the resulting
chain of two or more amino acids.
precursor:
Something that precedes.
1.
In biological processes, a substance from which another, usually
more active or mature substance is formed.
2. In clinical medicine, a sign or symptom that heralds another.
Origin: L. precursor = a forerunner
pituitary:
An endocrine gland located at the base of the brain, in the
small recess of a bone - certain sections of the pituitary each
secretes important hormones including growth hormone (GH) and
antidiuretic hormone (ADH).
polypeptide:
A peptide which on hydrolysis yields more than two amino acids,
called tripeptides, tetrapeptides, etc. According to the number
of amino acids contained.
somatotropin-releasing
hormone:
hypothalamic peptide that regulates the synthesis and secretion
of somatotropin in the anterior pituitary gland.
Chemical name: Somatoliberin
secretagogue:
Substance that induces secretion from cells, originally applied
to peptides inducing gastric and pancreatic secretion.
somatomedins:
Insulin-like polypeptides made by the liver and some fibroblasts
and released into the blood when stimulated by somatotropin.
They cause sulfate incorporation into collagen, RNA, and DNA
synthesis, which are prerequisites to cell division and growth
of the organism.
somatostatin:
Gastrointestinal and hypothalmic peptide hormone (two forms:
14 and 28 residues), found in gastric mucosa, pancreatic islets,
nerves of the gastrointestinal tract, in posterior pituitary
and in the central nervous system. Inhibits gastric secretion
and motility: in hypothalamus/pituitary inhibits somatotropin
release.
somatotrophin:
growth hormone, somatotropin.
somatotropin:
Hormone (191 amino acids) released by anterior pituitary that
stimulates release of somatomedin, thereby causing growth.
An amino acid based substance secreted by the pituitary gland
that promotes cell growth and maintenance, stimulates the immune
system, etc. [See Human Growth
Hormone]
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somatropin:
synthetic or naturally occurring growth hormone from the human
pituitary gland. It is given to children with open epiphyses
for the treatment of pituitary dwarfism. Chemical name: Somatotropin
(human)
